Taking metronidazole for bacterial vaginosis– 500mg or 1000mg per day?


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I was prescribed metronidazole for bacterial vaginosis. When the doctor was writing the prescription I could’ve sworn she said "take this once a day," but when I filled the prescription, I noticed that the bottle said to take twice daily. The tablets are 500mg strength. There are 14 tablets, so it seems reasonable that I would take them twice a day rather than once. What is the typical dosage in this situation?

One Reply to “Taking metronidazole for bacterial vaginosis– 500mg or 1000mg per day?”

  1. Bacterial vaginosis
    a) Guideline Recommendation
    1) The CDC-recommended dose of oral metronidazole for non-pregnant women is 500 mg orally twice daily for 7 days (Workowski & Berman, 2006).
    2) The CDC-recommended dose of metronidazole for pregnant women is metronidazole 500 mg ORALLY twice daily or 250 mg ORALLY 3 times daily for 7 days (Workowski & Berman, 2006).

    Generally ER (extended release) tablets are taken once daily.

    b) Manufacturer Recommendation
    1) The approved dose of metronidazole extended release tablets for the treatment of bacterial vaginosis is 750 milligrams orally once daily for 7 days (Prod Info FLAGYL(R) ER extended-release oral tablets, 2003).

    You should call your doctor and clarify.

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